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Article

Bax- and Bak-induced cell death in the fission yeast Schizosaccharomyces pombe.

Molecular biology of the cell - 1 Feb 1997

Jürgensmeier J M, Krajewski S, Armstrong R C, Wilson G M, Oltersdorf T, Fritz L C, Reed J C, Ottilie S

Abstract excerpt

The effects of the expression of the human Bcl-2 family proteins Bax, Bak, Bcl-2, and Bcl-XL were examined in the fission yeast Schizosaccharomyces pombe and compared with Bax-induced cell death in mammalian cells. Expression of the proapoptotic proteins Bax and Bak conferred a lethal phenotype in this yeast, which was strongly suppressed by coexpression of the anti-apoptotic protein Bcl-XL. Bcl-2 also partially...

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Identifiers

PMID: 9190211
DOI: 10.1091/mbc.8.2.325
PMCID: PMC276083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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