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Article

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells.

Molecular and cellular biology - 1 Nov 1996

Zha H, Fisk H A, Yaffe M P, Mahajan N, Herman B, Reed J C

Abstract excerpt

Expression of the proapoptotic protein Bax under the control of a GAL10 promoter in Saccharomyces cerevisiae resulted in galactose-inducible cell death. Immunofluorescence studies suggested that Bax is principally associated with mitochondria in yeast cells. Removal of the carboxyl-terminal transmembrane (TM) domain from Bax [creating Bax (deltaTM)] prevented targeting to mitochondrial and completely abolished...

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Identifiers

PMID: 8887678
DOI: 10.1128/MCB.16.11.6494
PMCID: PMC231651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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