Article
Apoptosis in yeast: a new model system with applications in cell biology and medicine.
Current genetics - 1 Jul 2002
Madeo Frank, Engelhardt Silvia, Herker Eva, Lehmann Nina, Maldener Corinna, Proksch Astrid, Wissing Silke, Fröhlich Kai-Uwe
Abstract excerpt
Apoptosis is a highly coordinated cellular suicide program crucial for metazoan health and diseases. Although its increasing importance in cancer, neurodegenerative disorders and AIDS led to intense research and a better understanding of apoptosis, many details of its regulation or the apoptotic phenotypes are poorly understood. The complex regulatory network and the often contradictory results obtained with...
Topics
- Aging
- Apoptosis
- Cell Cycle
- Eukaryotic Cells
- Forecasting
- Gene Expression
- Gene Expression Regulation, Fungal
- Hydrogen Peroxide
- Models, Biological
- Mutation
- Oxidative Stress