Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death.

Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 2000

Igaki T, Kanuka H, Inohara N, Sawamoto K, Núñez G, Okano H, Miura M

Abstract excerpt

The Bcl-2/CED-9 family of proteins, which includes both antiapoptotic and proapoptotic members, plays key regulating roles in programmed cell death. We report here the identification and characterization of Drob-1, the first Drosophila member of the Bcl-2/CED-9 family to be isolated. Drob-1 conta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis Regulatory Proteins
Share to Caspases
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helminth Proteins

Share to Insect Proteins

Share to Intracellular Membranes

Share to Proto-Oncogene Proteins c-bcl-2

Source

Open in PubMed Open full text

Identifiers

PMID: 10639136
DOI: 10.1073/pnas.97.2.662
PMCID: PMC15387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10639136-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death.PMID 10639136Read ↗

Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery.Semantic proximity Read ↗

The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death.Semantic proximity Read ↗

The Human Bcl-2 Family Member Bcl-rambo Localizes to Mitochondria and Induces Apoptosis and Morphological Aberrations in Drosophila.Semantic proximity Read ↗

Bax‐like protein Drob‐1 protects neurons from expanded polyglutamine‐induced toxicity in DrosophilaSemantic proximity Read ↗

Genetic control of programmed cell death (apoptosis) in Drosophila.Semantic proximity Read ↗

A genome-wide RNAi screen reveals multiple regulators of caspase activationSemantic proximity Read ↗

Bcl-B, a Novel Bcl-2 Family Member That Differentially Binds and Regulates Bax and BakSemantic proximity Read ↗

Apoptosis in Drosophila: which role for mitochondria?Semantic proximity Read ↗

DCP-1, a Drosophila cell death protease essential for development.Semantic proximity Read ↗

Mitochondria and apoptosisSemantic proximity Read ↗

Intrinsic apoptosis is evolutionarily divergent among metazoansSemantic proximity Read ↗

drICE is an essential caspase required for apoptotic activity in Drosophila cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.