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Article

Modulation of cell death in yeast by the Bcl-2 family of proteins.

The Journal of biological chemistry - 13 Jun 1997

Tao W, Kurschner C, Morgan J I

Abstract excerpt

Bcl-2 family members are regulators of cell death. The precise biochemical properties of these proteins are unclear although intrafamily protein-protein association is thought to be involved. To elucidate structure-activity relationships among Bcl-2 proteins and identify the pathways in which they act, an inducible death suppressor assay was developed in yeast. Only Bax and Bak killed yeast via a process that did...

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PMID: 9182591
DOI: 10.1074/jbc.272.24.15547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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