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Article

Role of the CCR5 delta 32 allele in resistance to HIV-1 infection in west Africa.

Journal of human virology - 1 Jan 2000

Kokkotou E, Philippon V, Guèye-Ndiaye A, Mboup S, Wang W K, Essex M, Kanki P

Abstract excerpt

OBJECTIVE: To determine the frequency of the mutant CCR5 delta 32 allele in high-risk HIV-seronegative Africans as compared with the general African population, and to assess its in vitro protective efficacy against HIV-1 infection. STUDY DESIGN: In the homozygous form, the CCR5 delta 32 allele confers resistance to macrophage-tropic (M-tropic) strains of HIV-1. Assuming that genetic characteristics favoring HIV...

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Source

Identifiers

PMID: 10195268

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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