Article
Protective effect of CCR5 Delta-32 allele against HIV-1 in Mexican women.
Current HIV research - 1 Sept 2013
Estrada-Aguirre Jesús A, Cázarez-Salazar Silvestre G, Ochoa-Ramírez Luis A, Acosta-Cota Selene de J, Zamora-Gómez Román, Najar-Reyes Guilermi M, Villarreal-Escamilla Perla, Osuna-Ramírez Ignacio, Díaz-Camacho Sylvia P, Sánchez-Zazueta Jorge G, Ríos-Tostado Juan J, Velarde-Félix Jesús S
Abstract excerpt
C-C chemokine receptor type 5 (CCR5) is known for its role as a co-receptor for HIV-1 infection. Some individuals possess a 32 bp deletion, known as Delta-32 allele which has been reported to confer resistance to HIV-1 infection. In order to estimate the distribution of Delta-32 allele of CCR5 gene, 1034 mestizo individuals from the Northwest of Mexico, including 385 HIV-1-infected individuals, 472 healthy...
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