Article
Evidence that a locus for familial psoriasis maps to chromosome 4q.
Nature genetics - 1 Oct 1996
Matthews D, Fry L, Powles A, Weber J, McCarthy M, Fisher E, Davies K, Williamson R
Abstract excerpt
Psoriasis is an inflammatory skin disease that affects 2% of the population. It is characterised by red, scaly skin patches which are usually found on the scalp, elbows and knees, and may be associated with severe arthropathy. The lesions are caused by abnormal keratinocyte proliferation, and infiltration of inflammatory cells into the dermis and epidermis. The usual age of onset of psoriasis is between 15 and 30...
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