Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening for the Gly40Ser mutation in the glucagon receptor gene among patients with type 2 diabetes or essential hypertension in Taiwan.

Pancreas - 1 Mar 1999

Huang C N, Lee K C, Wu H P, Tai T Y, Lin B J, Chuang L M

Abstract excerpt

As a major counterregulatory hormone of insulin, glucagon plays an important role in regulating glucose homeostasis through its binding to the glucagon receptor. Recently a missense mutation in the glucagon-receptor gene (Gly40Ser) was found to be associated with type 2 diabetes in France and Sardinia, with a frequency as high as 4.6% and 8.3%, respectively. This mutation was also found to be associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Blood Glucose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Diabetes Mellitus, Type 2

Share to Hypertension

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Glucagon

Share to Taiwan

Source

Identifiers

PMID: 10090412
DOI: 10.1097/00006676-199903000-00006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for the Gly40Ser mutation in the glucagon receptor gene among patients with type 2 diabetes or essential hypertension in Taiwan.PMID 10090412Read ↗

Glucagon receptor Gly40Ser amino acid variant in Sardinian hypertensive non-insulin-dependent diabetic patients. Sardinian Diabetic Genetic Study Group (SDGSG).Semantic proximity Read ↗

Restricted geographical extension of the association of a glucagon receptor gene mutation (Gly40Ser) with non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

[Gly40Ser mutation of glucagon receptor gene and NIDDM in Han nationality].Semantic proximity Read ↗

Physiological and genetic characterization of the Gly40Ser mutation in the glucagon receptor gene in the Sardinian population. The Sardinian Diabetes Genetic Study Group.Semantic proximity Read ↗

Glucagon receptor gene mutation (Gly40Ser) in human essential hypertension: the PEGASE study.Semantic proximity Read ↗

Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland.Semantic proximity Read ↗

Absence of the Gly40-ser mutation in the glucagon receptor gene in Japanese subjects with NIDDM.Semantic proximity Read ↗

The Gly482Ser variant of the PPARGC1 gene is associated with Type 2 diabetes mellitus in northern Chinese, especially men.Semantic proximity Read ↗

Association of Trp64Arg beta 3-adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population.Semantic proximity Read ↗

Nucleotide(-258) G-to-A transition variant of the liver glucokinase gene is associated with essential hypertension.Semantic proximity Read ↗

Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders.Semantic proximity Read ↗

Trp64Arg mutation of beta3-adrenergic receptor in essential hypertension: insulin resistance and the adrenergic system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.