Article
Absence of the Gly40-ser mutation in the glucagon receptor gene in Japanese subjects with NIDDM.
Diabetes research and clinical practice - 1 Jul 1996
Ogata M, Iwasaki N, Ohgawara H, Karibe S, Omori Y
Abstract excerpt
Recent studies have shown both association and linkage between a Gly40-Ser mutation in the glucagon receptor gene and NIDDM in French patients with familial NIDDM. This mutation was present in heterozygous form in 4.6% of diabetic probands but only 1% of the French population, suggesting that it was an important risk factor in the development of NIDDM. A total of 348 unrelated Japanese subjects (220 with NIDDM,...
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