Article
Absence of the Gly40-ser mutation in the glucagon receptor gene in Japanese subjects with NIDDM.
Diabetes research and clinical practice - 1 Jul 1996
Ogata M, Iwasaki N, Ohgawara H, Karibe S, Omori Y
Abstract excerpt
Recent studies have shown both association and linkage between a Gly40-Ser mutation in the glucagon receptor gene and NIDDM in French patients with familial NIDDM. This mutation was present in heterozygous form in 4.6% of diabetic probands but only 1% of the French population, suggesting that it...
Topics
- Adult
- Aged
- Asian People
- Autoradiography
- Diabetes Mellitus, Type 2
- Electrophoresis, Polyacrylamide Gel
- Female
- Gene Frequency
- Glucose Intolerance
- Humans
- Japan
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Glucagon