Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Damage to the transforming growth factor TGF-beta type II receptor gene and microsatellite instability in carcinoma cells of the gastrointestinal tract].

Voprosy onkologii - 1 Jan 1998

Vostriukhina O A, Nikiforova I F, Shtam T A, Kantorov S L, Kovalev V K, Vasil'ev S V, Pozharisskiī K M, Lantsov V A

Abstract excerpt

In order to compare the frequency of damage to the transforming growth factor TGF-beta receptor type II gene (RII gene) and microsatellite instability (MIN) in oncogenesis of sporadic and hereditary cancer of gastrointestinal tract (GIT), 4 groups of carcinomas were analyzed. They included sporadic gastric (GC), family gastric (FGC), sporadic colorectal (CC) and hereditary nonpolyposis colorectal (HNPCC)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Progression

Share to DNA Damage

Share to DNA, Neoplasm

Share to Gastrointestinal Neoplasms

Share to Receptors, Transforming Growth Factor beta

Share to Stomach Neoplasms

Source

Identifiers

PMID: 10087960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Damage to the transforming growth factor TGF-beta type II receptor gene and microsatellite instability in carcinoma cells of the gastrointestinal tract].PMID 10087960Read ↗

[Microsatellite instability of genome in cells of sporadic and hereditary carcinoma of the gastrointestinal tract].Semantic proximity Read ↗

[Genetic alterations in human malignant tumor].Semantic proximity Read ↗

Analyses of microsatellite instability and the transforming growth factor-beta receptor type II gene mutation in sporadic human gastrointestinal cancer.Semantic proximity Read ↗

The somatic mutation frequency of the transforming growth factor beta receptor type II gene varies widely among different cancers with microsatellite instability.Semantic proximity Read ↗

Microsatellite instability and mutations of p53 and TGF-beta RII genes in gastric cancer.Semantic proximity Read ↗

Alterations of transforming growth factor-beta 1 receptor type II occur in ulcerative colitis-associated carcinomas, sporadic colorectal neoplasms, and esophageal carcinomas, but not in gastric neoplasms.Semantic proximity Read ↗

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.Semantic proximity Read ↗

Analyses of mutation and loss of heterozygosity of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human gastric cancer.Semantic proximity Read ↗

Mutation of the transforming growth factor-beta type II receptor gene is a rare event in human sporadic gastric carcinomas.Semantic proximity Read ↗

Promoter methylation of TGFbeta receptor I and mutation of TGFbeta receptor II are frequent events in MSI sporadic gastric carcinomas.Semantic proximity Read ↗

Mutations of the transforming growth factor-beta type II receptor gene are strongly related to sporadic proximal colon carcinomas with microsatellite instability.Semantic proximity Read ↗

Microsatellite instability in gastric cancer prone families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.