Article
[Genetic alterations in human malignant tumor].
Rinsho byori. The Japanese journal of clinical pathology - 1 Jan 1999
Tomita S, Muto Y, Kusano T, Toda T
Abstract excerpt
To clarify the genetic background of cancer patients, microsatellite instability (MSI) and mutations of transforming growth factor-beta type II receptor (RII), p53 and k-ras gene were investigated. MSI were detected in 33.3% of esophageal, 15.8% of gastric, 21.4% of colorectal, 4.5% of bile duct, 0% of gallbladder, 13.3% of pancreatic, 11.6% of breast and 10.5% of thyroid cancers. Mutations of RII gene were...
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