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Article

Regulation of actin organisation by TGF-β in H-ras-transformed fibroblasts

15 Apr 1999

Abstract excerpt

The actin cytoskeleton undergoes architectural changes during the processes of cell transformation and tumourigenesis. Transforming growth factors beta arrest cell cycle progression, regulate differentiation and modulate the onset of oncogenesis and tumourigenesis. Here, we investigated the direct role of transforming growth factor beta-1 in altering the transformed phenotype and regulating the actin organisation...

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Identifiers

PMID: 10085252
DOI: 10.1242/jcs.112.8.1169

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Source receipt: pubmed, retrieved 7 Sept 2026.

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