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Article

Role of proteoglycans and cytoskeleton in the effects of TGF-beta 1 on renal proximal tubule cells.

Kidney international - 1 Mar 1993

Humes H D, Nakamura T, Cieslinski D A, Miller D, Emmons R V, Border W A

Abstract excerpt

Transforming growth factor-beta (TGF-beta) is a critical cell regulatory protein which influences cell growth, cell differentiation and cell chemotaxis. TGF-beta 1 has been previously shown to promote a migratory and adherent transformation of monolayers of renal proximal tubule cells in primary culture to form solid clusters of cells. To better understand the cellular basis of this TGF-beta 1 effect, these...

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PMID: 8455356
DOI: 10.1038/ki.1993.85

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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