Article
Induction of anchorage independent growth and serum resistance in immortalized human bronchial epithelial cells by alteration of the cytoskeleton.
Cellular & molecular biology research - 1 Jan 1994
De Silva R, Englezou A, Schevzov G, Gerwin B I, Harris C C, Gunning P, Reddel R R
Abstract excerpt
Malignant transformation is frequently accompanied by obvious changes in cytoarchitecture, but the importance of these changes has been difficult to assess in view of the large number of other cellular changes that also occur. In this study, we transfected the SV40-immortalized human bronchial epithelial cell line, BEAS-2B, with human wild-type beta or gamma actin gene expression plasmids to induce cytoskeletal...
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