Article
Connexin diversity and gap junction regulation by pHi.
Developmental genetics - 1 Jan 1999
Francis D, Stergiopoulos K, Ek-Vitorín J F, Cao F L, Taffet S M, Delmar M
Abstract excerpt
The molecular mechanisms controlling pH-sensitivity of gap junctions formed of two different connexins are yet to be determined. We used a proton-sensitive fluorophore and electrophysiological techniques to correlate changes in intracellular pH (pHi) with electrical coupling between connexin-expressing Xenopus oocytes. The pH sensitivities of alpha 3 (connexin46), alpha 2 (connexin38), and alpha 1 (connexin43)...
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