Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chimeric evidence for a role of the connexin cytoplasmic loop in gap junction channel gating.

Pflugers Archiv : European journal of physiology - 1 Apr 1996

Wang X, Li L, Peracchia L L, Peracchia C

Abstract excerpt

Gap junction channels are regulated by gates that close upon exposure to 100% CO2, probably via an increase in intracellular Ca2+ concentration, [Ca2+]i. For defining connexin (Cx) domain(s) involved in gating, we have studied chemical and voltage gating sensitivities of channels made of Cx38, Cx...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cytoplasm
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen-Ion Concentration

Share to Ion Channel Gating

Share to Mutation

Share to Oocytes

Share to Recombinant Fusion Proteins

Source

Identifiers

PMID: 8927500
DOI: 10.1007/s004240050076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8927500-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chimeric evidence for a role of the connexin cytoplasmic loop in gap junction channel gating.PMID 8927500Read ↗

Is the chemical gate of connexins voltage sensitive? Behavior of Cx32 wild-type and mutant channels.Semantic proximity Read ↗

Altered CO2 sensitivity of connexin26 mutant hemichannels in vitro.Semantic proximity Read ↗

Unusual slow gating of gap junction channels in oocytes expressing connexin32 or its COOH-terminus truncated mutant.Semantic proximity Read ↗

Opposing modulation of Cx26 gap junctions and hemichannels by CO <sub>2</sub>Semantic proximity Read ↗

Calmodulin-Cork Model of Gap Junction Channel Gating-One Molecule, Two Mechanisms.Semantic proximity Read ↗

Connexin26 hemichannels with a mutation that causes KID syndrome in humans lack sensitivity to CO2.Semantic proximity Read ↗

Gating of cx46 gap junction hemichannels by calcium and voltage.Semantic proximity Read ↗

Diversity and molecular anatomy of gap junctions.Semantic proximity Read ↗

Calmodulin Binding to Connexin 35: Specializations to Function as an Electrical Synapse.Semantic proximity Read ↗

Engineered Cx40 variants increased docking and function of heterotypic Cx40/Cx43 gap junction channels.Semantic proximity Read ↗

Gap junction channel structure in the early 21st century: facts and fantasies.Semantic proximity Read ↗

Voltage-dependent conformational changes in connexin channels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.