Codon bias and mutability in HIV sequences.

doi:10.1007/pl00006483

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Article

Codon bias and mutability in HIV sequences.

Journal of molecular evolution - 1 Apr 1999

Stephens C R, Waelbroeck H

Abstract excerpt

A survey of the patterns of synonymous codon preference in the HIV env gene reveals a correlation between the codon bias and the mutability requirements of different regions of the protein. At hypervariable regions in gp120 one finds a greater proportion of codons that tend to mutate nonsynonymou...

Topics

Codon
Genes, env
HIV
Mutation

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