Article
Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations.
Neuroscience letters - 5 Feb 1999
Houlden H, Rizzu P, Stevens M, de Knijff P, van Duijn C M, van Swieten J C, Heutink P, Perez-Tur J, Thomas V, Baker M, Morris H, Rossor M, Jannsen J C, Petersen R C, Dodd P, Dark F, Boeve B, Dickson D, Davies P, Pickering-Brown S, Mann D, Adamson J, Lynch T, Payami H, Hardy J
Abstract excerpt
We have assessed whether apolipoprotein E (ApoE) genotype influences the age of onset of dementia in a series of families with frontal temporal dementia with defined mutations in the tau gene. In contrast to the situation in Alzheimer's disease (AD), we could find no evidence that the age of onset of disease was influenced by the ApoE genotype.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.