Article
Apolipoprotein E in sporadic and familial Creutzfeldt-Jakob disease.
Neuroscience letters - 20 Oct 1995
Salvatore M, Seeber A C, Nacmias B, Petraroli R, D'Alessandro M, Sorbi S, Pocchiari M
Abstract excerpt
We assessed the apolipoprotein E (ApoE) genotype in 49 sporadic and ten familial Creutzfeldt-Jakob disease (CJD) patients, in seven healthy siblings with a PRNP mutation and in 84 controls. In sporadic CJD, ApoE genotypes and allelic frequencies do not significantly differ from that of controls. No influence of ApoE genotypes on age at onset was found. In familial cases, the disease appeared in mutated subjects...
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