Article
Genetic interaction between YPT6 and YPT1 in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 1 Jul 1998
Li B, Warner J R
Abstract excerpt
Ypt6p, the yeast homologue of human RAB6, is required for protein trafficking at elevated temperatures. Biochemical data provide evidence that Ypt6p plays a role in an early step(s) of the secretory pathway: from ER to Golgi, or from cis to medial Golgi, or both. Here we show that overexpression of YPT1 suppresses the growth and secretion defects of a ypt6 temperature-sensitive (ts) strain. SLY1-20, encoding a...
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