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Article

Modular TRAPP complexes regulate intracellular protein trafficking through multiple Ypt/Rab GTPases in Saccharomyces cerevisiae.

Genetics - 1 Jun 2012

Zou Shenshen, Liu Yutao, Zhang Xiu Qi, Chen Yong, Ye Min, Zhu Xiaoping, Yang Shu, Lipatova Zhanna, Liang Yongheng, Segev Nava

Abstract excerpt

Ypt/Rab are key regulators of intracellular trafficking in all eukaryotic cells. In yeast, Ypt1 is essential for endoplasmic reticulum (ER)-to-Golgi transport, whereas Ypt31/32 regulate Golgi-to-plasma membrane and endosome-to-Golgi transport. TRAPP is a multisubunit complex that acts as an activator of Ypt/Rab GTPases. Trs85 and Trs130 are two subunits specific for TRAPP III and TRAPP II, respectively. Whereas...

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Identifiers

PMID: 22426882
DOI: 10.1534/genetics.112.139378
PMCID: PMC3374310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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