Association of Ki-ras mutation with differentiation and tumor-formation pathways in colorectal carcinoma.

doi:10.1002/ijc.2910490213

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Article

Association of Ki-ras mutation with differentiation and tumor-formation pathways in colorectal carcinoma.

International journal of cancer - 9 Sept 1991

Laurent-Puig P, Olschwang S, Delattre O, Validire P, Melot T, Mosseri V, Salmon R J, Thomas G

Abstract excerpt

The occurrence of a point mutation on the 12th and 13th codons of the Ki-ras oncogene has been investigated in 99 colorectal carcinomas in relation to 3 histological parameters: extent of differentiation, occurrence of a mucinous component within the tumor, and presence of peripheral adenomatous...

Topics

Adenocarcinoma, Mucinous
Base Sequence
Codon
Colonic Polyps
Colorectal Neoplasms
Genes, ras
Humans
Middle Aged
Molecular Sequence Data
Mutation

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