Article
Alloreactivity and association of human natural killer cells with the major histocompatibility complex.
Clinical and diagnostic laboratory immunology - 1 Mar 1999
Mavoungou E, Sall A, Poaty-Mavoungou V, Toure F S, Yaba P, Delicat A, Lansoud-Soukate J
Abstract excerpt
All NK cells potentially lytic for autologous cells but not expressing self-major histocompatibility complex (MHC)-reactive receptors could be eliminated by a negative selection mechanism during ontogeny. This idea is based on the existence of a NK cell subset expressing a specific inhibitory receptor for allogeneic MHC alleles. As ancestral haplotypes of the MHC appear to define identical MHC haplotypes in...
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