Article
Independent contributions of HLA epitopes and killer inhibitory receptor expression to the functional alloreactive specificity of natural killer cells.
Human immunology - 1 Nov 1998
Young N T, Rust N A, Dallman M J, Cerundolo V, Morris P J, Welsh K I
Abstract excerpt
Human NK cells express receptors (KIR) which inhibit lysis through binding to HLA class I on target cells. KIR expression in different individuals has not been intensively investigated and it is not known how the KIR repertoire relates to HLA type or influences the overall activity of NK populations. This may be important in the response of NK cells to HLA-mismatched organ transplants since the ligands for KIR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
