Article
Independent contributions of HLA epitopes and killer inhibitory receptor expression to the functional alloreactive specificity of natural killer cells.
Human immunology - 1 Nov 1998
Young N T, Rust N A, Dallman M J, Cerundolo V, Morris P J, Welsh K I
Abstract excerpt
Human NK cells express receptors (KIR) which inhibit lysis through binding to HLA class I on target cells. KIR expression in different individuals has not been intensively investigated and it is not known how the KIR repertoire relates to HLA type or influences the overall activity of NK populati...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Antibodies, Monoclonal
- Antigens, CD
- Cell Line
- Cytotoxicity, Immunologic
- Epitopes
- Flow Cytometry
- Genotype
- HLA Antigens
- HLA-D Antigens
- Histocompatibility Antigens Class I