Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Typing of 4AOHW cells by allospecific natural killer cells.

Human immunology - 1 Sept 1993

Thomsen M, Witt C S, Degli-Esposti M A, Christiansen F T

Abstract excerpt

Alloreactivity of human NK cells was tested on a subset of the 4AOHW cell panel. A total of 37 cells were typed with NK clones reactive with the NK-1, 2, 3, and 5 allospecificities. No cell was susceptible to lysis by both by anti-NK-1 and anti-NK-2 clones in accordance with the notion of a biallelic system, where the susceptibility toward lysis is a recessive trait. HLA homozygous cells were lysed either by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Clone Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heterozygote

Share to Homozygote

Share to Molecular Sequence Data

Share to Polymorphism, Genetic

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 8307787
DOI: 10.1016/0198-8859(93)90519-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Typing of 4AOHW cells by allospecific natural killer cells.PMID 8307787Read ↗

HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells.Semantic proximity Read ↗

Role of Natural Killer Cell Alloreactivity in HLA-Mismatched Hematopoietic Stem Cell TransplantationSemantic proximity Read ↗

Generation of allospecific natural killer cells by stimulation across a polymorphism of HLA-C.Semantic proximity Read ↗

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.Semantic proximity Read ↗

The reactivity of Bw4+ HLA-B and HLA-A alleles with KIR3DL1: implications for patient and donor suitability for haploidentical stem cell transplantationsSemantic proximity Read ↗

Rapid, flow cytometric assay for NK alloreactivity reveals exceptions to rules governing alloreactivity.Semantic proximity Read ↗

NK cell-mediated lysis of autologous HCMV-infected skin fibroblasts is highly variable among NK cell clones and polyclonal NK cell lines.Semantic proximity Read ↗

Alloreactivity and association of human natural killer cells with the major histocompatibility complex.Semantic proximity Read ↗

Comprehensive Analysis of Cytomegalovirus pp65 Antigen-Specific CD8+ T Cell Responses According to Human Leukocyte Antigen Class I Allotypes and Intraindividual DominanceSemantic proximity Read ↗

Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules.Semantic proximity Read ↗

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).Semantic proximity Read ↗

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.