Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The serotonin transporter gene (5-HTT) variant and psychiatric disorders: review of current literature.

Neuro endocrinology letters - 1 Jan 2010

Kuzelova Hana, Ptacek Radek, Macek Milan

Abstract excerpt

Both serotonin and the serotonin transporter, which transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons, play an important role in the pathophysiology of several psychiatric disorders. Mutations associated with the serotonin transporter gene may result in changes in serotonin transporter function. The serotonin transporter gene promoter variant, consisting of a long (L) and a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Developmental Disabilities
Share to Feeding and Eating Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mental Disorders

Share to Mood Disorders

Share to Mutant Proteins

Share to Self-Injurious Behavior

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 20150867

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The serotonin transporter gene (5-HTT) variant and psychiatric disorders: review of current literature.PMID 20150867Read ↗

Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapySemantic proximity Read ↗

Clinical Implications of Genetic Variation in the Serotonin Transporter Promoter RegionSemantic proximity Read ↗

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region.Semantic proximity Read ↗

Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants.Semantic proximity Read ↗

Effects of serotonin transporter and receptor polymorphisms on depression.Semantic proximity Read ↗

An update on the interaction between the serotonin transporter promoter variant (5-HTTLPR), stress and depression, plus an exploration of non-confirming findings.Semantic proximity Read ↗

Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets.Semantic proximity Read ↗

Serotonin transporter gene polymorphisms, alcoholism, and suicidal behavior.Semantic proximity Read ↗

Functional polymorphism in the serotonin transporter promoter at the SLC6A4 locus and mood disorders.Semantic proximity Read ↗

Association between violent suicidal behavior and the low activity allele of the serotonin transporter gene.Semantic proximity Read ↗

The serotonin transporter promoter polymorphism and suicide.Semantic proximity Read ↗

The serotonin transporter gene and risk for alcohol dependence: a meta-analytic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.