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Article

Lymph node germinal centers form in the absence of follicular dendritic cell networks.

The Journal of experimental medicine - 1 Mar 1999

Koni P A, Flavell R A

Abstract excerpt

Follicular dendritic cell networks are said to be pivotal to both the formation of germinal centers (GCs) and their functions in generating antigen-specific antibody affinity maturation and B cell memory. We report that lymphotoxin beta-deficient mice form GC cell clusters in the gross anatomical location expected of GCs, despite the complete absence of follicular dendritic cell networks. Furthermore,...

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Identifiers

PMID: 10049949
DOI: 10.1084/jem.189.5.855
PMCID: PMC2192950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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