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Article

Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei.

Antimicrobial agents and chemotherapy - 1 Mar 1999

Moore R A, DeShazer D, Reckseidler S, Weissman A, Woods D E

Abstract excerpt

Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to a wide range of antimicrobial agents including beta-lactams, aminoglycosides, macrolides, and polymyxins. We used Tn5-OT182 to mutagenize B. pseudomallei to identify the genes involved in aminoglycoside resistance. We report here on the identification of AmrAB-OprA, a multidrug efflux system in B. pseudomallei which is...

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Identifiers

PMID: 10049252
DOI: 10.1128/AAC.43.3.465
PMCID: PMC89145

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Source receipt: pubmed, retrieved 7 Sept 2026.

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