Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Basis of Rare Aminoglycoside Susceptibility and Pathogenesis of Burkholderia pseudomallei Clinical Isolates from Thailand

21 Sept 2009

Abstract excerpt

BACKGROUND: Burkholderia pseudomallei is intrinsically resistant to aminoglycosides and macrolides, mostly due to AmrAB-OprA efflux pump expression. We investigated the molecular mechanisms of aminoglycoside susceptibility exhibited by Thai strains 708a, 2188a, and 3799a. METHODOLOGY/PRINCIPAL FINDINGS: qRT-PCR revealed absence of amrB transcripts in 708a and greatly reduced levels in 2188a and 3799a. Serial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Burkholderia infections and melioidosis
Share to Plant Pathogenic Bacteria Studies
Share to Research on Leishmaniasis Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19771149
DOI: 10.1371/journal.pntd.0000519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Basis of Rare Aminoglycoside Susceptibility and Pathogenesis of Burkholderia pseudomallei Clinical Isolates from ThailandPMID 19771149Read ↗

A Novel Amino Acid Deletion and Substitution in <i>amrB</i> Gene Associated with Gentamicin Susceptibility in <i>Burkholderia pseudomallei</i> from Malaysian BorneoSemantic proximity Read ↗

Identification and mechanism determination of the efflux pump subunit amrB gene mutations linked to gentamicin susceptibility in clinical Burkholderia pseudomallei from Malaysian Borneo.Semantic proximity Read ↗

Burkholderia pseudomallei Isolates from Sarawak, Malaysian Borneo, Are Predominantly Susceptible to Aminoglycosides and MacrolidesSemantic proximity Read ↗

Eﬄux pump-mediated drug resistance in BurkholderiaSemantic proximity Read ↗

Multi-locus sequence typing and genetic diversity of antibiotic-resistant genes and virulence-associated genes in Burkholderia pseudomallei: Insights from whole genome sequencing of animal and environmental isolates in Thailand.Semantic proximity Read ↗

Genomics and structural insight into the masking of gentamicin-resistance in clinical Burkholderia pseudomallei strain VB29710 from India.Semantic proximity Read ↗

Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse – a case report.Semantic proximity Read ↗

Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei.Semantic proximity Read ↗

Genome-wide association study of antibiotic resistance in clinical Burkholderia pseudomallei strains from Hainan province, ChinaSemantic proximity Read ↗

Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse.Semantic proximity Read ↗

Antibiotic Susceptibility of Clinical Burkholderia pseudomallei Isolates in Northeast Thailand from 2015 to 2018 and the Genomic Characterization of β -Lactam-Resistant IsolatesSemantic proximity Read ↗

Involvement of the efflux pumps in chloramphenicol selected strains of Burkholderia thailandensis: proteomic and mechanistic evidence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.