Article
Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD.
Developmental biology - 1 Aug 2009
Kanisicak Onur, Mendez Julio J, Yamamoto Shoko, Yamamoto Masakazu, Goldhamer David J
Abstract excerpt
Satellite cells are tissue-specific stem cells responsible for skeletal muscle growth and regeneration. Although satellite cells were identified almost 50 years ago, the identity of progenitor populations from which they derive remains controversial. We developed MyoD(iCre) knockin mice, and used Cre/lox lineage analysis to determine whether satellite cell progenitors express MyoD, a marker of myogenic...
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