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Article

Three-dimensional structure of a recombinant gap junction membrane channel.

Science (New York, N.Y.) - 19 Feb 1999

Unger V M, Kumar N M, Gilula N B, Yeager M

Abstract excerpt

Gap junction membrane channels mediate electrical and metabolic coupling between adjacent cells. The structure of a recombinant cardiac gap junction channel was determined by electron crystallography at resolutions of 7.5 angstroms in the membrane plane and 21 angstroms in the vertical direction. The dodecameric channel was formed by the end-to-end docking of two hexamers, each of which displayed 24 rods of...

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Identifiers

PMID: 10024245
DOI: 10.1126/science.283.5405.1176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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