Article

Chemical probes of surface layer biogenesis in Clostridium difficile

2011-01-01

Abstract excerpt

The bacterium Clostridium difficile is responsible for recent epidemics of gastroenteritis and currently causes over twice as many deaths per year as the other major hospital ‘superbug’, MRSA. Since the bacterium is resistant to conventional antibiotics there is an urgent need to develop novel therapies. C. difficile secretes a family of proteins that are held in place on the cell wall by non-covalent forces, prod...

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Literature Corpus work: ff864fab-321b-51db-9ae1-9b409d7e6c23
DOI: 10.25560/6870

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