Article

Junctional adhesion molecular 3 (JAM3) is a novel tumor suppressor and improves the prognosis in breast cancer brain metastasis via the TGF-β/Smad signal pathway

2024-08-11

Abstract excerpt

<title>Abstract</title> <p>Purpose The incidence of breast cancer brain metastasis (BCBM) is a deadly clinical problem, and exact mechanisms remain elusive. Junction adhesion molecule (JAM), a tight junction protein, is a key negative regulator of cancer cell invasion and metastasis. Methods Junction adhesion molecular 3 (JAM3) expression in breast cancer was analyzed by bioinformatics method and confirmed by P...

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Literature Corpus work: ff7d86a8-b789-5433-9e8e-b44638339db0
DOI: 10.21203/rs.3.rs-4727537/v1

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