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microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy

14 Feb 2020

Abstract excerpt

Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth factor 2 (HER2)-positive breast cancer (BC) patients, and currently, there is an unmet need for the treatment of these patients. BM is a complex process that is regulated by the formation of a metastatic niche. A better understanding of the brain metastatic processes and the crosstalk between cancer cells and brain...

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PMID: 32059676
DOI: 10.1186/s12943-020-1140-x

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