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Tight Junction Protein Signaling and Cancer Biology

6 Jan 2023

Abstract excerpt

Tight junctions (TJs) are intercellular protein complexes that preserve tissue homeostasis and integrity through the control of paracellular permeability and cell polarity. Recent findings have revealed the functional role of TJ proteins outside TJs and beyond their classical cellular functions as selective gatekeepers. This is illustrated by the dysregulation in TJ protein expression levels in response to...

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PMID: 36672179
DOI: 10.3390/cells12020243

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