Article

CILP Inhibits Brain Metastasis by Meditating Mast Cells via the MAPK Signaling Pathway in Breast Cancer

2021-03-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Approximately 15–30% of patients with breast cancer (BRCA) eventually develop brain metastases (BMs) with high morbidity and mortality. Herein, we aimed to identify genes specific to breast cancer brain metastases (BCBM) from an immune infiltration perspective.<bold>Methods: </bold>GSE100534 and GSE125989 were obtained from the NCBI Gene Expression Omnibus (GEO)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 380ad436-e288-5136-9180-4996f0095140
DOI: 10.21203/rs.3.rs-328026/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CILP Inhibits Brain Metastasis by Meditating Mast Cells via the MAPK Signaling Pathway in Breast CancerDOI 10.21203/rs.3.rs-328026/v1Read

CILP, a Putative Gene Associated With Immune Infiltration in Breast Cancer Brain MetastasesSemantic proximity Read

PI3K: A master regulator of brain metastasis‐promoting macrophages/microgliaSemantic proximity Read

Screening and Identification of Key Biomarkers in Breast Cancer with Brain Metastasis: Evidence from Bioinformatic AnalysisSemantic proximity Read

Screening and identification of key biomarkers in breast cancer with brain metastasis: Evidence from bioinformatic analysisSemantic proximity Read

Identification of potential genes related to breast cancer brain metastasis in breast cancer patientsSemantic proximity Read

DIRAS3, GPR171 and RAC2 were identified as the key molecular patterns associated with brain metastasis of breast cancerSemantic proximity Read

ceRNA Network Development and Tumour-infiltrating Immune Cell Analysis in Metastatic Breast Cancer of BoneSemantic proximity Read

Junctional adhesion molecular 3 (JAM3) is a novel tumor suppressor and improves the prognosis in breast cancer brain metastasis via the TGF-β/Smad signal pathwaySemantic proximity Read

ceRNA network development and tumour-infiltrating immune cell analysis of metastatic breast cancer to boneSemantic proximity Read

Insights into the Steps of Breast Cancer–Brain Metastases Development: Tumor Cell Interactions with the Blood–Brain BarrierSemantic proximity Read

Identification of Key Genes Related to Lung Cancer with Brain Metastasis through Weighted Gene Correlation Network AnalysisSemantic proximity Read

microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in TherapySemantic proximity Read