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Article

Cooperative expression of junctional adhesion molecule‐C and ‐B supports growth and invasion of glioma

30 Sept 2009

Abstract excerpt

Brain invasion is a biological hallmark of glioma that contributes to its aggressiveness and limits the potential of surgery and irradiation. Deregulated expression of adhesion molecules on glioma cells is thought to contribute to this process. Junctional adhesion molecules (JAMs) include several IgSF members involved in leukocyte trafficking, angiogenesis, and cell polarity. They are expressed mainly by...

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PMID: 19795504
DOI: 10.1002/glia.20941

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