Article

Airborne Nanoplastics Perturb Mitochondrial Complex I via the ND6 Axis: Polymer-Specific Mitoepigenetic Remodeling Integrating Experimental, In Silico, and Machine Learning Analyses

2025-12-19

Abstract excerpt

Airborne nanoplastics constitute an emerging class of environmental contaminants, but their mitoepigenetic effects on human immune cells have not been systematically investigated. Ex vivo human lymphocytes were used to investigate integrated mitochondrial, epigenetic, and inflammatory responses induced by polystyrene (PS), polypropylene (PP), and polyvinyl chloride (PVC) nanoplastics. Fluorescence microscopy at mu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0af0c336-55da-5a8e-84a3-3459ce3b5eb8
DOI: 10.64898/2025.12.19.695405

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Airborne Nanoplastics Perturb Mitochondrial Complex I via the ND6 Axis: Polymer-Specific Mitoepigenetic Remodeling Integrating Experimental, In Silico, and Machine Learning AnalysesDOI 10.64898/2025.12.19.695405Read

Polystyrene microplastic uptake drives Inflammatory, Epitranscriptomic, and Metabolic Reprogramming in Human Aortic Endothelial cellsSemantic proximity Read

Environmental Chemical Exposures and Mitochondrial Dysfunction: a Review of Recent LiteratureSemantic proximity Read

Oxidative Stress, Environmental Pollutants, Aging, and Epigenetic Regulation: Mechanistic Insights and Biomarker AdvancesSemantic proximity Read

Hallmarks of environmental insults.Semantic proximity Read

From Mutation to Metabolism: Environmental and Dietary Toxins as Upstream Drivers of Mitochondrial Dysfunction and Chronic DiseaseSemantic proximity Read

Phthalate Exposure Induces Inflammatory Signaling and Suppresses Mitochondrial Function in Marine Mammal and Human CellsSemantic proximity Read

Lipophilic Chemical Accumulation, a Systems Level Driver of Chronic Disease. An Integrated Multi-Omics and Toxicokinetic FrameworkSemantic proximity Read

Chronic exposure to low-concentration urban PM2.5 accelerates maladaptive repair after ischemic injury via mitochondrial dysfunction and lysosomal stressSemantic proximity Read

Revealing toxic secrets: How PAHs accelerate cellular ageing and trigger human diseasesSemantic proximity Read

Microplastics from disposable paper cups are enriched in the placenta and fetus, leading to metabolic and reproductive toxicity during pregnancySemantic proximity Read

Mitochondrial-epigenetic crosstalk in environmental toxicology.Semantic proximity Read

Susceptibility to COVID‐19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutantsSemantic proximity Read