Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of SIRT1-mediated aging in liver diseases

20 Feb 2025

Abstract excerpt

Liver disease is a significant global health issue, responsible for millions of deaths annually. Aging, characterized by the gradual decline in cellular and physiological functions, impairs tissue regeneration, increases susceptibility to liver diseases, and leads to a decline in liver health. Silent information regulator 1 (SIRT1), a NAD⁺-dependent deacetylase, has emerged as a pivotal factor in modulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical effects in animals
Share to Genomics, phytochemicals, and oxidative stress
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40052151
DOI: 10.3389/fcell.2025.1548015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of SIRT1-mediated aging in liver diseasesPMID 40052151Read ↗

The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic targetSemantic proximity Read ↗

Aging and Aging-Related Senescence in LiverSemantic proximity Read ↗

SIRT1 and SIRT6: The role in aging-related diseasesSemantic proximity Read ↗

Targeting SIRT2 in Aging-Associated Fibrosis PathophysiologySemantic proximity Read ↗

Mechanisms and disease implications of sirtuin-mediated autophagic regulationSemantic proximity Read ↗

SIRT7: the seventh key to unlocking the mystery of agingSemantic proximity Read ↗

Role of sirtuins in epigenetic regulation and aging controlSemantic proximity Read ↗

From Sirtuin Biology to Human Diseases: An UpdateSemantic proximity Read ↗

SIRT3/6: an amazing challenge and opportunity in the fight against fibrosis and agingSemantic proximity Read ↗

SIRTain regulators of premature senescence and accelerated agingSemantic proximity Read ↗

Mammalian Sirtuins: Biological Insights and Disease RelevanceSemantic proximity Read ↗

Sirtuins and their Biological Relevance in Aging and Age-Related DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.