Article

The microenvironment of ulcerated acral melanoma is characterised by an inflammatory milieu and an enhanced humoral immune response

2025-05-07

Abstract excerpt

Acral melanoma (AM) is a distinct and understudied subtype of melanoma that is reported to represent the majority of melanoma diagnoses in various Latin American, African and Asian countries. Patients with ulcerated AM diagnoses face a worse prognosis and increased risk of recurrence. While tumour ulceration has been shown to influence therapy response in cutaneous melanoma patients, the clinical and molecular tra...

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Literature Corpus work: 90f10754-e17c-509a-a11a-57ec06dc0ac1
DOI: 10.1101/2025.05.05.25325616

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