Article

PI3K regulates intraepithelial cell positioning through Rho GTP-ases in the developing neural tube

2017-08-21

Abstract excerpt

<h4>SUMMARY STATEMENT</h4> During neural tube development, PI3K pathway promotes cell survival and provides the apical-basal navigation clues that define the final location of neurons in the epithelium. <h4>SUMMARY</h4> Phosphatidylinositol 3-kinases (PI3Ks) are signal transducers of many biological processes. Class 1A PI3Ks are hetero dimers formed by a regulatory and a catalytic subunit. We have used the devel...

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Literature Corpus work: ff23c335-6685-56c5-8e59-09c635cebce2
DOI: 10.1101/179325

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