Article

Tracking Replicating HPV Genomes in Proliferating Keratinocytes

2025-03-19

Abstract excerpt

Human papillomavirus (HPV) genomes replicate and partition as minichromosomes alongside host chromatin during persistent infection. However, it is difficult to monitor genome dynamics in living cells because the small and compact genome will not easily tolerate expression cassettes. Here, we use ANCHOR™ technology to detect HPV18 genomes in living cells. We incorporated the cis element from ANCHOR TM technology i...

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Literature Corpus work: ff1dec17-2614-599d-8172-a7deceacbcf9
DOI: 10.1101/2025.03.18.644043

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