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Article

The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression

2021-05-01

Abstract excerpt

<h4>ABSTRACT</h4> The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries, stabilise chromatin loops and regulate splicing of alternative exons. We have previously demonstrated that CTCF binds to the E2 open reading frame (ORF) of human papillomavirus (HPV) 18 and functions to repress viral oncogene expression in...

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Literature Corpus work
e73fea9d-d9d3-5966-a301-29c5f8a687c0
DOI
10.1101/2021.04.30.442078
Open publication

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The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expressionDOI 10.1101/2021.04.30.442078
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