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AI-Driven Spatial Transcriptomics Unlocks Large-Scale Breast Cancer Biomarker Discovery from Histopathology

2024-10-18

Abstract excerpt

Spatial transcriptomics (ST) is transforming our understanding of tumor heterogeneity by enabling high-resolution, location-specific mapping of gene expression across tumors and their microenvironment. However, the associated high cost of the assay has limited cohort size and hence large-scale biomarker discovery. Here we present Path2Space , a deep learning approach that predicts spatial gene expression directly...

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Literature Corpus work: 6c1f3bf2-4df8-53af-9c39-646ba10c46aa
DOI: 10.1101/2024.10.16.618609

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