Article

Plasma regulates homeostatic pulmonary endothelial signaling to mitigate vascular leak following polytrauma and hemorrhagic shock

2026-03-04

Abstract excerpt

<h4>Introduction</h4> In hemorrhagic shock, plasma resuscitation preserves vascular integrity and protects against trauma-induced coagulopathy and organ injury. Despite demonstrated clinical benefit, the endothelial mechanisms underlying plasma resuscitation remain incompletely defined. This study investigated endothelial-specific responses to plasma resuscitation to identify targetable pathways that promote vasc...

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Literature Corpus work: fef05cef-a225-5ef0-b07e-75ad1484dcac
DOI: 10.64898/2026.03.04.709561

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