Article

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice

2025-03-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Severe injury, including burn trauma, leads to profound immune dysfunction, yet the mechanisms driving these changes remain incompletely defined. This lack of understanding has hindered efforts to modulate the immune response effectively. Additionally, a clear biomarker profile to guide clinicians in identifying burn patients at high risk for poor clinical outcomes is lack...

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Literature Corpus work: b1d08295-534b-5bd2-bacd-91603f346d7f
DOI: 10.1101/2025.03.19.644202

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