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CInvestigating the Mechanism of the Co - regulation of Colorectal Cancer by Tumor - associated Fibroblasts and Disulfidptosis Based on Single - cell RNA Sequencing and Bulk RNA Sequencing

2026-06-24

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<title>Abstract</title> <p>Background The roles of cancer-associated fibroblasts (CAFs) and disulfidptosis in colorectal cancer (CRC) remain unclear. Methods Using single-cell RNA sequencing (scRNA-seq) and disulfidptosis-related genes (DRGs), we analyzed CRC datasets (TCGA-CRC, GSE87211, GSE132257). CAFs were extracted from scRNA-seq for pseudotime analysis. Differentially expressed genes (DEGs) from scRNA-seq...

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Literature Corpus work
d3338657-b471-587a-9d28-07cf8be7b7aa
DOI
10.21203/rs.3.rs-9734066/v1
Open publication

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CInvestigating the Mechanism of the Co - regulation of Colorectal Cancer by Tumor - associated Fibroblasts and Disulfidptosis Based on Single - cell RNA Sequencing and Bulk RNA SequencingDOI 10.21203/rs.3.rs-9734066/v1
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