Article

IsoCon: Deciphering highly similar multigene family transcripts from Iso-Seq data

2018-01-10

Abstract excerpt

A significant portion of genes in vertebrate genomes belongs to multigene families, with each family containing several gene copies whose presence/absence can be highly variable across individuals. For example, each Y chromosome ampliconic gene family harbors several nearly identical (up to 99.99%) gene copies. Existing de novo techniques for assaying the sequences of such highly-similar gene families fall short...

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Literature Corpus work: fe14fac9-bc9a-5264-af9f-a70676553693
DOI: 10.1101/246066

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