Back to search

Article

The capsule and genetic background, rather than specific individual loci, strongly influence <i>in vitro</i> pneumococcal growth kinetics

2024-12-05

Abstract excerpt

Bacterial growth characteristics intrinsic to each strain can impact and influence gene expression, antibiotic susceptibility, and disease pathogenesis. However, little is known about specific genomic variations that influence these bacterial growth features. Here, we investigate the impact of Streptococcus pneumoniae genetics on its in vitr o growth features to shed light on genes that may be important targets...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fde248f4-072f-5f77-b0e5-11e7bc3a328d
DOI
10.1101/2024.12.05.627025
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The capsule and genetic background, rather than specific individual loci, strongly influence <i>in vitro</i> pneumococcal growth kineticsDOI 10.1101/2024.12.05.627025
Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration.Semantic proximity
The contribution of genetic variation of <i>Streptococcus pneumoniae</i> to the clinical manifestation of invasive pneumococcal diseaseSemantic proximity
Pneumococcal genetic variability influences age-dependent bacterial carriageSemantic proximity
Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage durationSemantic proximity
Population genomics of Group B Streptococcus reveals the genetics of neonatal disease onset and meningeal invasionSemantic proximity
Genome-wide association, prediction and heritability in bacteriaSemantic proximity
Adding context to the pneumococcal core genes – a bioinformatic analysis of the intergenic pangenome of <i>Streptococcus pneumoniae</i>Semantic proximity
The Contribution of Genetic Variation of Streptococcus pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease.Semantic proximity
LacR and TrxB are key virulence factors involved in pneumococcal meningitis as identified by a genome-wide association studySemantic proximity
High-dimensional Characterization of Genome–Environment Fitness Landscapes in <i>Klebsiella pneumoniae</i>Semantic proximity
A soluble host signal drives rapid, brain-predominant capsular thickening in <i>Streptococcus pneumoniae</i> via a putative sodium-dependent transporter (SPD_0642) and capsular prepromoter sequenceSemantic proximity
A phasevarion controls multiple virulence traits, including expression of vaccine candidates, in <i>Streptococcus pneumoniae</i>Semantic proximity
Select a neighboring publication to make it the new centre.